Among the orally disintegrating forms, Lozenges are solid preparations that are intended to dissolve or disintegrate slowly in the mouth. They contain one or more medicaments, usually in a flavoured, sweetened base. They can be prepared by molding (gelatin and/or fused sucrose or sorbitol base) or by compression of sugar-based tablets. Molded lozenges are sometimes referred to as Pastilles while compressed lozenges are often referred to as Troches. They are usually intended for treatment of local irritation or infections of the mouth or throat but may contain active ingredients intended for systemic absorption after swallowing. Molded lozenges have a softer texture because they contain a high percentage of sugar or a combination of a gelatin and sugar.
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